| ORIGINAL ARTICLE |
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| Year : 2021 | Volume
: 9
| Issue : 3 | Page : 108-113 |
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Stereological and histological assessment of the umbilical cord in new-born rat
Berrin Zuhal Altunkaynak1, Ahmad Yahyazadeh2
1 Department of Histology and Embryology, Medicine Faculty, Okan University, Istanbul, Turkey
2 Department of Histology and Embryology, Medicine Faculty, Karabuk University, Karabuk, Turkey
Correspondence Address:
Ahmad Yahyazadeh
Department of Histology and Embryology, Faculty of Medicine, Karabuk University, Karabu
Turkey
 Source of Support: None, Conflict of Interest: None  | 2 |
DOI: 10.4103/JMAU.JMAU_14_20
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Background: Umbilical cord plays a crucial role in the continuation of pregnancy by transferring nutrition and oxygen across the placenta to the fetus. We aimed to investigate the morphometrical and histological features of the umbilical cords in new-born rats. Materials and Methods: The adult male and female rats were chosen for matting purpose in the present study. Briefly, ten adult Wistar albino rats (female, n = 5; male, n = 5) were randomly assigned into five groups of two animals (female, n = 1; male, n = 1). Immediately after parturition, two umbilical cords of new-born rats (0-day-old) from each group were randomly selected. Finally, ten umbilical cord samples were examined using the histological and stereological methods in the light and electron microscopes. Results: The total numbers of Hofbauer cells and mesenchymal stromal cells was estimated statistically. We also calculated the mean volume of umbilical cords, arteries and veins, as well as arterial and venous lumens. Our histological findings also exhibited the histological features of Hofbauer cells, mesenchymal stromal cell cells, and blood vessels. Conclusion: Our findings showed more detailed information about umbilical cord tissues and their components, and that may contribute to the diagnose of umbilical cord complications in the developing fetus.
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