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Fundamentals of superparamagnetic iron oxide nanoparticles: Recent update


1 Department of Pharmaceutics, Sanjivani Institute of Pharmaceutical Education and Research, Kopargaon, India
2 Department of Pharmaceutics, Sanjivani Institute of Pharmaceutical Education and Research, Kopargaon; Department of Pharmaceutics, School of Pharmaceutical Sciences, Sandip University, Nashik, Maharashtra, India

Correspondence Address:
Abhijeet Dattatraya Kulkarni,
Department of Pharmaceutics, School of Pharmaceutical Sciences, Sandip University, Nashik - 422 213, Maharashtra
India
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmau.jmau_17_22

The medical sciences have mirrored the rapid growth of nanotechnology in recent years. Superparamagnetic iron oxide nanoparticles (IONPs) are a good example. Owing to its unique features, for example, superparamagnetism, higher surface area, surface-to-volume fraction, facile uncoupling methods, and IONPs have recently received a great deal of focus. Magnetic nanoparticles (NPs) with appropriate Surface chemistry have been created utilizing a range of physical and chemical methods. The IONPs employed in bioscience, health aid, environmental rehabilitation, and other domains were examined. The surface stabilization of IONPs with different stabilizers is explained in this review. This review discusses the necessary characterization of IONPs using multiple qualitative and quantitative methodologies in biological activity, which is beneficial owing to biodegradability and biocompatibility, simplicity of production, and magnetic behavior. This review covers practically all methods of IONP synthesis, size, and morphology, as well as their latest applications in many domains. With the present significance of Fe NPs, the current review aims to provide best of the information on the production, characterization, and uses of these NPs.


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